Effects of β-Blockers and Nicardipine on Oxotremorine-Induced Tremor in Common Marmosets

この論文にアクセスする

この論文をさがす

著者

抄録

Effects of β-blockers (propranolol, arotinolol and nipradilol) and a Ca<SUP>2+</SUP> channel blocker (nicardipine) on oxotremorine-induced tremor were studied in common marmosets. Generalized tremor was elicited by an intraperitoneal administration of 0.25 mg/kg oxotremorine. Intensity of the tremor was classified into 7 degrees, and it was evaluated every 10 min. The total intensity of oxotremorine-induced tremor for each drug was expressed as "points", which were the sum of tremor intensity scores evaluated every 10 min up to 190 min following the administration of oxotremorine. β-Blockers significantly suppressed the tremor. On the other hand, the Ca<SUP>2+</SUP> channel blocker exacerbated the tremor.

収録刊行物

  • The Japanese journal of pharmacology

    The Japanese journal of pharmacology 81(2), 244-246, 1999-10

    The Japanese Pharmacological Society

参考文献:  15件中 1-15件 を表示

各種コード

  • NII論文ID(NAID)
    10008197072
  • NII書誌ID(NCID)
    AA00691188
  • 本文言語コード
    ENG
  • 資料種別
    SHO
  • ISSN
    00215198
  • NDL 記事登録ID
    4886743
  • NDL 雑誌分類
    ZS51(科学技術--薬学)
  • NDL 請求記号
    Z53-D199
  • データ提供元
    CJP書誌  NDL  J-STAGE 
ページトップへ