酵素法によるオリゴ糖鎖ライブラリーの構築 Preparation of Oligosaccharide Units Library Utilizing Enzyme-catalyzed Glycosylation

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著者

    • 村田 健臣 MURATA Takeomi
    • 静岡大学農学部応用生物化学科 Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University
    • 碓氷 泰市 USUI Taichi
    • 静岡大学農学部応用生物化学科 Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University

抄録

With the growing biological importance of oligosaccharides involved in glycoconjugates, practical synthetic methods for obtaining oligosaccharides have been required. Enzyme-catalyzed oligosaccharide synthesis has been shown to be one of the most effective methods for large-scale oligo-saccharide synthesis. This review describes enzyme-catalyzed synthesis of di, tri, and tetrasaccharide units, which are related to biological roles: (1) galactose-containing disaccharides, (2) fucosecontaining trisaccharides, (3) core oligosaccharides in mucin-type carbohydrate, and (4) human milk oligosaccharides. Such well-defined oligosaccharide units are useful as substrates for glycosidases and glycosyltransferases, and as starting materials for artificial glycopolymers, which are valuable as probes of carbohydrate-protein interaction.

収録刊行物

  • 応用糖質科学 : oyo toshitsu kagaku = Journal of applied glycoscience

    応用糖質科学 : oyo toshitsu kagaku = Journal of applied glycoscience 47(2), 253-260, 2000-06-30

    The Japanese Society of Applied Glycoscience

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各種コード

  • NII論文ID(NAID)
    10008251973
  • NII書誌ID(NCID)
    AN10453916
  • 本文言語コード
    JPN
  • 資料種別
    REV
  • ISSN
    13403494
  • NDL 記事登録ID
    5436148
  • NDL 雑誌分類
    ZP24(科学技術--化学・化学工業--糖・澱粉)
  • NDL 請求記号
    Z17-15
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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