In vitro effect of carp phagocytic cells by bisphenol A and nonylphenol.

• GUSHIKEN YOSHIKI

  Faculty of Agriculture, Miyazaki University

• WATANUKI HIRONOBU

  Faculty of Agriculture, Miyazaki University

• SAKAI MASAHIRO

  Faculty of Agriculture, Miyazaki University

抄録

The effect of bisphenol A and nonylphenol on carp Cyprinus carpio phagocytic cells was analyzed in vitro. Head kidney leukocytes of carp were exposed to 10 nM of bisphenol A or nonylphenol, separately. Subsequently, the production of superoxide anions was measured via the reduction of nitroblue tetrazolium (NBT) in vitro. Macrophages incubated with 0.1 nM up to 10 nM of bisphenol showed an increase in the production of superoxide anions in comparison with the control macrophages, which were not treated with bisphenol A. Nonylphenol also induced the production of superoxide anions in phagocytic cells prepared from carp kidney. Phagocytic cells treated with both bisphenol A and nonylphenol decreased phagocytic activity. However, the production of nitric oxide in carp macrophages did not change when treated only with either bisphenol A or nonylphenol. These results indicate that bisphenol A and nonylphenol affected the function of phagocytic cells in vitro.

収録刊行物

• Ｆｉｓｈｅｒｉｅｓ　ｓｃｉｅｎｃｅ

  Ｆｉｓｈｅｒｉｅｓ　ｓｃｉｅｎｃｅ 68 (1), 178-183, 2002

  公益社団法人 日本水産学会

キーワード

• bisphenol A
• carp
• macrophage
• nonylphenol
• phagocytosis

詳細情報

• CRID: 1390282679406376576
• NII論文ID: 130003742406
• NII論文ID: 10008272578
• NII書誌ID: AA10993718
• DOI: 10.1046/j.1444-2906.2002.00405.x
• ISSN: 14442906
• ISSN: 09199268
• NDL書誌ID: 6060574
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I6060574
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可