The usefulness and limitations of certain methods of measuring the plasma refilling rate in the patients undergoing hemodialysis.

• Yamanaka Nozomu

  Kitasato University Graduate School

• Fujimori Aki

  Kitasato University Graduate School

• Nambu Masahito

  Kidney Center, Kitasato University Hospital

• Saka Satoshi

  Saka Clinic

• Sakurai Kenji

  Hashimoto Clinic

• Moriya Rika

  Kitasato University School of Medicine

• Higashihara Masaaki

  Kitasato University Graduate School Kitasato University School of Medicine

• Kamata Kouju

  Kitasato University Graduate School Kidney Center, Kitasato University Hospital Kitasato University School of Medicine

Bibliographic Information

Other Title

• ヘマトクリット値連続測定装置を用いた各種ｐｌａｓｍａ　ｒｅｆｉｌｌｉｎｇ　ｒａｔｅ測定法の有用性と限界の検討

Abstract

[Aim] Althought the plasma refilling rate (PRR) during a hemodialysis (HD) session can be estimated by the CRIT-LINE^TM monitor (CLM), the optimal methods for measuring the PRR has not been established. Then, we investigate 11 methods for measuring the PRR to find an adequate and useful method. [Patients and Methods] Patients with stable blood pressure during HD participated in this study. Eleven methods of measuring the PRR using a combination of three patterns (UF-A, -B and -C) of ultrafiltration profile and a biometry method (8% method) and four kinds of recursion methods (Hct I method, ΔBV% I method, Hct II method and ΔBV% II method) for the effective blood volume (BV₍₀₎) at the start of an HD session were investigated. [Results] The PRR values were reflected in the three different ultrafiltration profiles. The PRR value obtained using the 8%-A method was 8.7±1.6mL/min. There was no significant difference between the PRR value obtained using the 8%-A method and that obtained using various BV₍₀₎ methods and the UF-C method. The PRR values measured using UF-B method were significantly lower than those measured using UF-A, or -C method (p<0.01, n=13). [Discussion] The PRR value obtained using the UF-A method is the value on ultrafiltration, while the PRR value obtained using the UF-B method is thought to be the physiological PRR. The UF-C method may be useful to determine the relationship between the colloid osmotic pressure and the PRR. The biometry method for obtaining the BV₍₀₎ showed an advantage for measuring the PRR throughout the HD session. [Conclusion] The 8%-A method is the best method for measuring PRR on ultrafiltration, and the 8%-B method is useful for measuring the PRR in the absence of ultrafiltration.

Journal

• Nihon Toseki Igakkai Zasshi

  Nihon Toseki Igakkai Zasshi 35 (2), 97-107, 2002

  The Japanese Society for Dialysis Therapy

Keywords

• plasma refilling rate
• CRIT-LINE^TM

Details

• CRID: 1390001204675866112
• NII Article ID: 130003721661
• NII Article ID: 10008362186
• NII Book ID: AN10432053
• DOI: 10.4009/jsdt.35.97
• ISSN: 1883082X
• ISSN: 13403451
• Web Site: https://search.jamas.or.jp/link/ui/2002209564
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed