Hepatocellular carcinoma developed in non-cirrhotic liver negative for hepatitis virus markers, 3 years after resection of tongue cancer

• ARAI Tatsuhiro

  Department of Gastroenterology, Tokyo Teishin Hospital

• HASHIMOTO Naoaki

  Department of Gastroenterology, Tokyo Teishin Hospital

• MATSUURA Hiroshi

  Department of Gastroenterology, Tokyo Teishin Hospital

• SAWATARI Takashi

  Department of Gastroenterology, Tokyo Teishin Hospital

• DEHARI Reiko

  Department of Gastroenterology, Tokyo Teishin Hospital

• SUZUKI Takeo

  Department of Radiology, Tokyo Teishin Hospital

• USHIJIMA Tatsujiro

  Department of Otolaryngology, Tokyo Teishin Hospital

• SEKIGAWA Kenichiro

  Department of Gastroenterology, Tokyo Teishin Hospital

• MATSUKAWA Masaya

  Department of Gastroenterology, Tokyo Teishin Hospital

• TAKAKURA Yuichi

  Department of Gastroenterology, Tokyo Teishin Hospital

• KORENAGA Tateo

  Department of Radiology, Tokyo Teishin Hospital

• MIURA Yasuo

  Department of Surgery, Social Insurance Central General Hospital

• BANDAI Yasutsugu

  Department of Surgery, Social Insurance Central General Hospital

• KITAMURA Shigehiro

  Department of Pathology, Social Insurance Central General Hospital

• KISHIDA Yukiko

  Department of Pathology, Tokyo Teishin Hospital

• YAMAZAKI Kazuto

  Department of Pathology, Tokyo Teishin Hospital

• YAKUMARU Kazuhiro

  Department of Pathology, Tokyo Teishin Hospital

Bibliographic Information

Other Title

• 舌癌切除３年後，異時性重複癌として肝炎ウイルスマーカー陰性の非硬変肝に発生した肝細胞癌の１切除例
• A case of double cancer

Abstract

68歳男性, 3年前舌癌 (stage I) 治癒切除の既往がある. 高血圧で受診中, ALP上昇から腹部超音波検査を施行され, 肝に径8cmの低エコー性腫瘤を指摘された. 慢性肝疾患はなく, 6kgの体重減少を自覚していた. 腫瘤は, CT上S6から尾側に突出する増強される単結節性腫瘤で, MRIではT1強調で等信号, T2強調でやや高信号. ⁶⁷Gaシンチで集積あり. 血中HBs抗原, HBc抗体, HCV抗体, HGV RNAはいずれも陰性, AFP 8ng/ml, PIVKA-II 1.4AU/mlだった. 上部下部消化管, 胆膵肺等に悪性腫瘍なし. 肝生検組織で一部に低分化を伴う中分化型肝細胞癌と診断された. 血管造影でも濃染し, 抗癌薬併用肝動脈塞栓療法と半年後の肝切除で治療され, 肝切除3年半後の現在健在である. 本例は, 舌癌切除の3年後, 異時性重複癌として, 肝炎ウイルスマーカー陰性の非硬変肝に発生した肝細胞癌で, 極めて稀な例と考えた.

Journal

• Kanzo

  Kanzo 43 (2), 125-130, 2002

  The Japan Society of Hepatology

Keywords

• 肝細胞癌
• 舌癌
• 重複癌

Details

• CRID: 1390001204790813440
• NII Article ID: 10008363198
• NII Book ID: AN00047770
• DOI: 10.2957/kanzo.43.125
• ISSN: 18813593
• ISSN: 04514203
• Web Site: http://www.jstage.jst.go.jp/article/kanzo1960/43/2/43_2_125/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2002146702
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed