書誌事項
- タイトル別名
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- Long-term progress of patients with chronic hepatitis B after administration of Lamivudine.
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抄録
The long-term prognosis of 34 patients with chronic hepatitis B after administration of Lamivudine (100mg/day) for 16∼52 weeks was examined. The median of the follow-up period after the treatment was 151 week (42∼172 week). The ALT levels normalized in 8 cases (24%) after the treatment. In 3 of the 8 cases, the amount of HBV DNA was low before the treatment, the ALT levels remained normal without an increase. On the other hand, in 5 of the 8 cases, after a transient increase in the ALT levels, the levels normalized. In the other 26 cases, the ALT levels fluctuated. These results suggested that long-term treatment using Lamivudine was required in most of the cases. However, this examination suggested that the necessary condition to discontinue Lamivudine was a low amount of HBV DNA before the treatment, HBe antibody positivity during the treatment, and HBV DNA negativity during the treatment. Further examinations in a larger number of patients should be performed.
収録刊行物
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- 肝臓
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肝臓 43 (3), 137-143, 2002
一般社団法人 日本肝臓学会
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詳細情報
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- CRID
- 1390001204790885376
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- NII論文ID
- 10008363238
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- NII書誌ID
- AN00047770
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- ISSN
- 18813593
- 04514203
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可