大腸癌の腫よう還流静脈血におけるＣＹＦＲＡ２１‐１測定の臨床的意義　　特に術後血行性再発の高危険因子としての意義

• 松本 浩

  東邦大学医学部外科学第一講座

書誌事項

タイトル別名

• Clinical Significance of the Mesenteric Blood Level of CYFRA21-1 in Patients with Colorectal Cancer. Patients at risk for postoperative hematogenous metastasis.
• Patients at risk for postoperative hematogenous metastasis
• 特に術後血行性再発の高危険因子としての意義

抄録

Abstract: Mesenteric blood levels of CYFRA21-1 were determined in 60 patients with primary colorectal cancer (Dukes A, 5 patients ; Dukes B, 28; Dukes C, 15; Dukes D, 12), and analyzed with respect to clinicopathological findings, postoperative hematogenous metastasis, and mesenteric blood levels of CEA. The present study found no correlation between CYFRA21-1 and CEA. Among clinicopathological parameters, patients with high mesenteric blood levels of CYFRA21-1 or CEA had a higher incidence of subserosal depth, lymph node metastasis, liver metastasis, and lymphatic vessel invasion. Discriminant analysis disclosed that the microvessel density, the mesenteric blood level of CYFRA21-1, and the peripheral blood level of CEA were significant predictors of a high risk group for postoperative hematogenous metastasis. In 47 patients with colorectal cancer, hematogenous metastasis was detected in 3 of the 4 patients in the high-risk group. These results suggested that the mesenteric blood level of CYFRA21-1 is useful for predicting postoperative hematogenous metastasis of colorectal cancer.

収録刊行物

• 日本大腸肛門病学会雑誌

  日本大腸肛門病学会雑誌 55 (3), 136-144, 2002

  日本大腸肛門病学会

キーワード

• 大腸癌
• CYFRA21-1
• 還流静脈血
• CEA
• 血行性再発

詳細情報

• CRID: 1390001204856686976
• NII論文ID: 10008386175
• NII書誌ID: AN00195100
• DOI: 10.3862/jcoloproctology.55.136
• ISSN: 18829619
• ISSN: 00471801
• Web Site: http://www.jstage.jst.go.jp/article/jcoloproctology1967/55/3/55_3_136/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2002180219
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可