増殖形態と肉眼型からみた大腸ｍｐ癌の臨床病理学的特徴

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  • Clinicopathological Features of Colorectal Cancer Invading the Muscularis Propria According to Growth Type and Macroscopic Type.

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We reviewed 54 patients with colorectal cancer invading the muscularis propria, to clarify the relationship between growth type and macroscopic type, and chnicopathological features. These were subclassified into two groups, and three groups, based on cross-section views : polypoid (PG) and nonpolypoid growth types (NPG) as to growth pattern, and protruding, intermediate, and deep ulcerated types as to macroscopic pattern. Twenty-nine cases were NPG, and 25 cases were PG. The depth of invasion of NPG was deeper than that of PG, although the mean size did not differ in the growth type. Cancers containing adenoma were more frequently PG than NPG. Lymph node metastasis was found in 28% of all the cases, in 20% of the cases in the colon, and in 38% of the cases in the rectum. There was no significant difference between growth type and macroscopic type, and lymph node metastasis. But, two cases with N2 station lymph node metastasis showed NPG. Four patients died due to cancer relapse, and all of them were rectal cancer with NPG. NPG cancer in the rectum appeared to have a malignant potential in mp colorectal cancer.

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