フォトトリコグラム法を用いた女性のびまん性脱毛症の定量的解析 Evaluation of Female Diffuse Alopecia by Image Analysis

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頭部のびまん性脱毛を主訴とする女性患者79人と健常女性27人の毛成長パターンを,非侵襲的なフォトトリコグラム法を用いて解析した.方法は頭頂部の頭髪を直径約1.5 cmの範囲ではさみで刈り,刈った直後と48時間後の画像から単位面積あたりの毛髪本数と長さを測定し,あわせて刈った頭髪の毛直径を測定した.その結果,びまん性脱毛を訴える患者は,正常コントロール群と同様のパターンを示す群(12.7%)と異常値群(87.3%)から成り,異常値群はさらに,毛の細い群,毛の伸びが遅い群,毛が細く伸びの遅い群,など7群に分類された.患者背景として,女性ホルモン補充療法4人(5.1%),ミクロゾームテスト陽性5人(6.3%),血清鉄低値9人(11.4%)などが含まれていた.本法は視診上異常を認めない程度の軽微な変化も検出することが可能で,女性のびまん性脱毛症の定量的評価や,脱毛の原因や予後を予測するために有用な方法と考えられた.

Growth patterns in scalp hair were studied in 79 Japanese female subjects (aged 17~66 y) complaining of diffuse scalp hair loss and in 27 normal Japanese female subjects (aged 24~53 y.o.). A combination of phototrichogram, a non-invasive quantitative method, and the measurement of hair shaft diameter by micrometer was used to calculate the rate of hair growth, the ratio of anagen hairs to the number of hairs per unit, the hair shaft diameter, and the percentages of thick and short hairs. The correlation between diffuse alopecia and other diseases, such as endocrine dysfunctions and anemia, was also assessed. Our quantitative analysis revealed that these 79 hair loss patients could be divided into eight categories on the basis of hair loss pattern. Ten of the 79 patients exhibited a normal hair growth pattern ; the remaining 69 had the hair loss patterns characterized by thinning only, low growth rate only, or low growth rate and thinning, none of which were previously distinguishable by unaided visual inspection. These results suggest that the method described above is useful for evaluating hair growth patterns in female patients complaining of diffuse scalp hair loss.

収録刊行物

  • 日本皮膚科学会雑誌

    日本皮膚科学会雑誌 112(1), 17-22, 2002-01-20

    Japanese Dermatological Association

参考文献:  19件中 1-19件 を表示

各種コード

  • NII論文ID(NAID)
    10008386404
  • NII書誌ID(NCID)
    AN00196602
  • 本文言語コード
    JPN
  • 資料種別
    ART
  • ISSN
    0021499X
  • NDL 記事登録ID
    025117254
  • NDL 請求記号
    Z19-202
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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