インターフェロン著効後，約６年の経過で発症した肝細胞癌の１例

• 坂田 直昭

  東北大学大学院消化器外科学

• 鈴木 正徳

  東北大学大学院消化器外科学

• 海野 倫明

  東北大学大学院消化器外科学

• 及川 昌也

  東北大学大学院消化器外科学

• 松野 正紀

  東北大学大学院消化器外科学

• 遠藤 希之

  東北大学病理部

書誌事項

タイトル別名

• A case of chronic hepatitis C developing from hepatocellular carcinoma 6 years after elimination of serum HCV RNA by interferon therapy.

抄録

We successfully resected hepatocellular carcinoma (HCC) developed about 6 years after elimination of serum HCV RNA by interferon (INF) therapy in a 59-year-old man with chronic hepatitis C. The route of infection with HCV was unknown. In 1994, the patient was pointed out having chronic hepatitis C and treated by INF at another hospital. As a result, HCV-RNA in the blood turned to negative and was maintained. Then, it was considered that HCV RNA was completely eliminated. About 6 years after the INF therapy, a mass 3cm in diameter was detected in the S8 lesion of the liver by an abdominal CT scan. A S8 subsegmentectomy involving the lesion was performed and measurements of tissue HCV-RNA were able to be measured in both cancer and non-cancer portions. There is a possibility that patients who have been infected with HCV and get negative conversion by INF therapy, develop to contract HCC. The close diagnostic imagings are indispensable for the patients who turned to negative in HCV-RNA by INF therapy.

収録刊行物

• 日本臨床外科学会雑誌

  日本臨床外科学会雑誌 62 (3), 761-766, 2001

  日本臨床外科学会

キーワード

• インターフェロン
• 肝細胞癌

詳細情報

• CRID: 1390001204845421568
• NII論文ID: 130003602388
• NII論文ID: 10008389027
• NII書誌ID: AA11189709
• DOI: 10.3919/jjsa.62.761
• ISSN: 18825133
• ISSN: 13452843
• ISSN: http://id.crossref.org/issn/13452843
• Web Site: http://www.jstage.jst.go.jp/article/ringe1998/62/3/62_3_761/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2001192151
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可