原発巣切除後早期に肝転移をしたα‐ｆｅｔｏｐｒｏｔｅｉｎ産生横行結腸癌の１例

DOI Web Site 被引用文献5件 参考文献23件

書誌事項

タイトル別名
  • A Case of .ALPHA.-fetoprotein Producing Cancer of the Transverse Colon with Early Hepatic Metastasis after Resection of the Primary Foci.

この論文をさがす

抄録

A 60-year-old man was admitted to the hospital because of general fatigue. On 40th day after a resection of α-fetoprotein (AFP) producing cancer of the transverse colon, serum AFP increased again and an abdominal CT scan revealed a hepatic tumor. With a diagnosis of metastatic hepatic cancer, a lateral segmentectomy was performed. Histologically it was poorly differentiated adenocarcinoma which was almost the same as the cancer of the transverse colon; a part of the poorly differentiated tissues was positive for AFP immunostaining. Serum elevated AFP level rapidly decreased and was in normal limit 2 months after the second operation. There have been no signs of metastasis or recurrence in the liver and other celiac organs as of 24 months after the second operation.<br> So far clinical cases of AFP-producing colorectal cancer have rarely been reported. Most of them had severe hepatic metatasis and the resultant poor prognosis. Only seven patients including our patient underwent hepatectomy, one of whom died of cancer 3 months after hepatectomy. In the treatment of AFP-producing gastrointestinal cancer, close exploration for hepatic metastasis must be made on a usual basis and an early start of strict observation of clinical course after operation is demanded by measuring serum AFP and using imaging procedures. Further, it is essential to measure serum AFP levels from preoperative period for the treatment of GI cancers.

収録刊行物

被引用文献 (5)*注記

もっと見る

参考文献 (23)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ