胃・卵巣転移を伴った乳腺浸潤性小葉癌の１例

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  • A case report of invasive lobular carcinoma of the breast with gastric and ovarian metastases.

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Invasive lobular carcinoma has a distinctive metastatic pattern compared with invasive ductal carcinoma. It has a higher tendency to metastasize to the stomach, intestine, ovary, peritoneum and retro-peritoneum. We report a rare case of invasive lobular carcinoma which metastasized to the stomach and ovary. A 46-year-old woman was seen at the hospital because of lower abdominal pain at defecation and epigastralgia at hunger. She also had a right breast mass. Radiological and endoscopic examinations showed bilateral ovarian tumors, multiple gastric ulcers and a linitis plastica lesion in the stomach. A biopsy specimen obtained from the stomach showed poorly differentiated adenocarcinoma. Simple mastectomy, total gastrectomy and bilateral oophorectomy were performed. Histological examination revealed that the gastric tumor spreaded between submucosal layer and serosa, and that both gastric and ovarian tumors were identical with the breast cancer. In the treatment of invasive lobular carcinoma, a systemic examination of the patient is mandatory taking its distinctive metastatic pattern in consideration.

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