単純泉における温泉療法による脱ストレス作用と免疫機能の変化 Stress Relieving Effect and Immunological Changes by Balneotherapy with a Simple Thermals

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It is reported that changes in immunological system are one of the underlining mechanisms of balneotherapy effects. Since there is no study concerning the mechanisms how balneotherapy with a simple thermals works, we tried to examine both the changes of immunological functions and stress relieving effect of balneotherapy. Fourteen inpatients (mean age 63 years) suffering from such as cerebrovascular diseases participated in the present study. Before and after 6-week balneotherapy, lymphocyte subset counts, levels of cytokines (IL-4, IL-6, IF-γ etc.) were determined and lymphocyte blastogenetic tests were also performed . In addition, stress barometers (urinary 17-ketosteroidsulfate (17KSS) / 17hydroxycorticosteroid (17OHCS)) were measured. As a result, no significant changes in cytokine levels were observed. Percentage of T cell count decreased and that of B cell increased. Percentage of suppressor T cell count decreased and that of helper and killer T cell tended to increase (not significant). Lymphocyte blastogenetic tests by ConA and PWM showed enhanced responses and urinary 17KSS / 170HCS levels increased after balneotherapy. From these findings, it is suggested that 6-week balneotherapy with a simple thermals has a potential of augmenting immunological functions and also possesses stress relieving effect.

It is reported that changes in immunological system are one of the underlining mechanisms of balneotherapy effects. Since there is no study concerning the mechanisms how balneotherapy with a simple thermals works, we tried to examine both the changes of immunological functions and stress relieving effect of balneotherapy. Fourteen inpatients (mean age 63 years) suffering from such as cerebrovascular diseases participated in the present study. Before and after 6-week balneotherapy, lymphocyte subset counts, levels of cytokines (IL-4, IL-6, IF-γ etc.) were determined and lymphocyte blastogenetic tests were also performed. In addition, stress barometers (urinary 17-ketosteroidsulfate (17KSS)/17hydroxycorticosteroid (17OHCS)) were measured. As a result, no significant changes in cytokine levels were observed. Percentage of T cell count decreased and that of B cell increased. Percentage of suppressor T cell count decreased and that of helper and killer T cell tended to increase (not significant). Lymphocyte blastogenetic tests by ConA and PWM showed enhanced responses and urinary 17KSS/17OHCS levels increased after balneotherapy. From these findings, it is suggested that 6-week balneotherapy with a simple thermals has a potential of augmenting immunological functions and also possesses stress relieving effect.

収録刊行物

  • 日本温泉気候物理医学会雑誌

    日本温泉気候物理医学会雑誌 65(3), 121-127, 2002-05-01

    日本温泉気候物理医学会

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被引用文献:  7件中 1-7件 を表示

各種コード

  • NII論文ID(NAID)
    10008426056
  • NII書誌ID(NCID)
    AN00186245
  • 本文言語コード
    JPN
  • 資料種別
    ART
  • ISSN
    00290343
  • NDL 記事登録ID
    6174871
  • NDL 雑誌分類
    ZS47(科学技術--医学--治療医学・看護学・漢方医学)
  • NDL 請求記号
    Z19-225
  • データ提供元
    CJP書誌  CJP引用  NDL  IR  J-STAGE 
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