Determination of a Common Clonal Origin of Gastric and Pulmonary Mucosa-Associated Lymphoid Tissue Lymphomas Presenting Five Years Apart.

DOI Web Site PubMed 被引用文献12件 参考文献15件
  • KAWAMATA Norihiko
    the First Department of Internal Medicine, Tokyo Medical and Dental University
  • MIKI Tohru
    the First Department of Internal Medicine, Tokyo Medical and Dental University
  • FUKUDA Tetsuya
    the First Department of Internal Medicine, Tokyo Medical and Dental University
  • SUZUKI Ken
    the First Department of Internal Medicine, Tokyo Medical and Dental University
  • SUMI Yuki
    the First Department of Internal Medicine, Tokyo Medical and Dental University
  • OHDAMA Shinichi
    the First Department of Internal Medicine, Tokyo Medical and Dental University
  • HIROSAWA Shinsaku
    the First Department of Internal Medicine, Tokyo Medical and Dental University
  • MATSUBARA Osamu
    the Second Division of Pathology, Tokyo Medical and Dental University
  • KAMIYAMA Ryuichi
    School of Allied Health Sciences, Tokyo Medical and Dental University
  • OKI Nobuo
    the First Department of Internal Medicine, Tokyo Medical and Dental University

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抄録

Mucosa-associated lymphoid tissue (MALT) lymphoma is often mis-diagnosed as a benign tumor. Dissemination to other sites occurs in MALT lymphoma. We report a 60-year-old man with gastric and pulmonary tumors of MALT lymphoma which occurred 5 years apart. Initially, the gastric tumor had been diagnosed as reactive lymphoreticular hyperplasia. To determine whether the two tumors arose from the same malignant clone, we amplified and sequenced the complementarity-determining region 3 of the immunoglobulin heavy chain gene using the polymerase chain reaction (PCR). The sequences were identical except for 11-nucleotide difference, suggesting identical clonality.<br>(Internal Medicine 34: 220-223, 1995)

収録刊行物

  • Internal Medicine

    Internal Medicine 34 (3), 220-223, 1995

    一般社団法人 日本内科学会

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