PTHrP-producing Tumor: Squamous Cell Carcinoma of the Liver Accompanied by Humoral Hypercalcemia of Malignancy, Increased IL-6 and Leukocytosis.

• ASANUMA Nobuyuki

  The Department of Internal Medicine, Aizenbashi Hospital

• HAGIWARA Keisuke

  The Department of Internal Medicine, Aizenbashi Hospital

• MATSUMOTO Ikuko

  The Department of Internal Medicine, Aizenbashi Hospital

• MATSUDA Masahiro

  The Department of Internal Medicine, Aizenbashi Hospital

• NAKAMURA Fumiaki

  The Department of Internal Medicine, Aizenbashi Hospital

• KOUHARA Haruhiko

  The Departments of Endocrinology, Osaka University Hospital

• MIYAMOTO Makoto

  The Departments of Pathology, Osaka University Hospital

• MIYASHITA Yoshihiro

  The Department of Internal Medicine, Aizenbashi Hospital

• NOGUCHI Sanai

  The Department of Internal Medicine, Aizenbashi Hospital

• MORIMOTO Yasuhiko

  The Department of Internal Medicine, Aizenbashi Hospital

抄録

A 77-year-old man was admitted to our hospital showing symptoms of general fatigue and appetite loss. He had leukocytosis, thrombocytosis and hypercalcemia with elevated serum levels of parathyroid hormone related peptide (PTHrP) and interIeukin-6 (IL-6). An increase in tumor markers SCC and CYFURA21-1 was observed. The liver contained a huge tumor, which was proved to be PTHrP producing squamous cell carcinoma by immuno-histochemical analysis. Since the tumor did not express IL-6, it was assumed to be induced by PTHrP in osteoblasts. This is the first report of PTHrP producing squamous cell carcinoma of the liver.<br>(Internal Medicine 41: 371-376, 2002)

収録刊行物

• Internal Medicine

  Internal Medicine 41 (5), 371-376, 2002

  一般社団法人 日本内科学会

キーワード

• calcium
• parathyroid hormone
• cytokine
• liver cyst

詳細情報

• CRID: 1390001204867997824
• NII論文ID: 10008450750
• NII書誌ID: AA10827774
• DOI: 10.2169/internalmedicine.41.371
• COI: 1:STN:280:DC%2BD38zhs1Grsw%3D%3D
• ISSN: 13497235
• ISSN: 09182918
• ISSN: http://id.crossref.org/issn/09182918
• NDL書誌ID: 6169560
• PubMed: 12058886
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I6169560
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine1992/41/5/41_5_371/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2002241439
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可