6-(Hydroxyalkyl)penicillanates as Probes for Mechanisms of β-Lactamases

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著者

    • GOLEMI Dasantila
    • Department of Chemistry and Institute for Drug Design, Wayne State University
    • MAVEYRAUD Laurent
    • Groupe de Cristallographie Biologique, Institut de Pharmacologie et de Biologie Structurale du CNRS
    • ISHIWATA Akihiro
    • Department of Chemistry and Institute for Drug Design, Wayne State University
    • TRANIER Samuel
    • Groupe de Cristallographie Biologique, Institut de Pharmacologie et de Biologie Structurale du CNRS
    • NAGASE Tsuyoshi
    • Department of Chemistry and Institute for Drug Design, Wayne State University
    • MASSOVA Irina
    • Department of Chemistry and Institute for Drug Design, Wayne State University
    • MOUREY Lionel
    • Groupe de Cristallographie Biologique, Institut de Pharmacologie et de Biologie Structurale du CNRS
    • SAMAMA Jean-Pierre
    • Groupe de Cristallographie Biologique, Institut de Pharmacologie et de Biologie Structurale du CNRS

抄録

6-(Hydroxyalkyl)penicillanates have proven helpful as probes for the mechanisms of β-lactamases, enzymes of resistance for β-lactam antibiotics. The present report summarizes the concepts on design, syntheses and use of these molecules in mechanistic studies of β-lactamases.

収録刊行物

  • Journal of antibiotics

    Journal of antibiotics 53(10), 1022-1027, 2000-10-25

    JAPAN ANTIBIOTICS RESEARCH ASSOCIATION

参考文献:  19件中 1-19件 を表示

各種コード

  • NII論文ID(NAID)
    10008468223
  • NII書誌ID(NCID)
    AA0069330X
  • 本文言語コード
    ENG
  • 資料種別
    REV
  • ISSN
    00218820
  • データ提供元
    CJP書誌  J-STAGE 
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