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- GAO QIANG
- Biology Department, Massachusetts Institute of Technology Present address: Department of Chemical Engineering, University of Colorado
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- DEMAIN ARNOLD L.
- Biology Department, Massachusetts Institute of Technology
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The bioconversion of penicillin G, an inexpensive substrate, to the valuable intermediate for semi synthetic cephalosporin production, deacetoxycephalosporin G (DAOG), had been recently shown to be increased by eliminating agitation and adding decane. The present work examining other solvents shows that all alkanes tested are equivalent to decane in activity but that other solvents are either inhibitory or less active than alkanes. Optimum conditions of pH and temperature for the alkane system are not very different from the previously used aqueous system.
収録刊行物
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- The Journal of Antibiotics
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The Journal of Antibiotics 54 (11), 958-961, 2001
公益財団法人 日本感染症医薬品協会
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詳細情報 詳細情報について
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- CRID
- 1390001204150900096
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- NII論文ID
- 130003410400
- 10008471420
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- NII書誌ID
- AA0069330X
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- COI
- 1:CAS:528:DC%2BD3MXovVOru7c%3D
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- ISSN
- 18811469
- 00218820
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- PubMed
- 11827038
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可