高齢者甲状腺原発非ホジキンリンパ腫の臨床的検討

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タイトル別名
  • Clinical Study of Elderly Patients with Non-Hodgkin's Lymphoma Arising in the Thyroid.
  • コウレイシャ コウジョウセン ゲンパツ ヒ ホジキン リンパシュ ノ リンショ

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The study group comprised 10 patients who were referred between 1992 and 1996 with non-Hodgkin's lymphoma arising in the thyroid gland. There were three men and seven women, with a median age of 75 years, and seven of the group had a history of Hashimoto's disease. All 10 patients had hypothyroidism; anti-microsomal antibody was positive in six. The lymphoma was of the diffuse type in all patients (B cell, 9: T cell, 1). Five patients had stage I and five had stage II.<br>Generally, four courses of COP-BLAM therapy were given, followed by radiotherapy (30Gy). Complete remission was achieved in all patients, and they remained alive and disease-free for a median period of 40 months.<br>Ultrasonography revealed diffuse, an-or hypoechoic confluent nodules, and there was intensification of the posterior acoustic enhancement in most patients.<br>With early diagnosis non-Hodgkin's lymphoma arising in the thyroid of elderly patients, mainly women, can be cured with chemotherapy and radiotherapy.

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