リンパ節転移例からみた大腸sm癌の治療方針についての検討

書誌事項

タイトル別名
  • PRINCIPLES OF TREATMENT FOR COLORECTAL CANCERS WITH SUBMUCOSAL INVASION-BASED ON A STUDY OF 90 OPERATED CASES WITH SUBMUCOSAL INVASION-

この論文をさがす

抄録

The purpose of this study was to determine the clinicopathological features of colorectal submucosal can-cers with lymph node metastasis and to investigate the principles of treatment for colorectal cancers with submucosal invasion. The subjects were 90 patients with primary colorectal submucosal cancer who underwent resection at our department between 1980 and 1997. Seven (7.8%) of 90 patients were histologically confirmed to have lymph node metastasis. According to the grouping of the regional lymph nodes proposed by the Japanese Research Society for Cancer of the Colon and Rectum, positive lymph nodes in the n 1 stations were observed in five patients. Two patients had positive nodes in the n 2 stations. None showed positive nodes in stations further than n 3. They were comprised of seven patients with lymph node metastasis (positive group) and 83 with no lymph node metastasis (negative group).<br>All of the patients with lymph node metastasis had sm 2 or sm 3 invasion, according to the criteria of submucosal invasion proposed by Kudo et al., and were positive for lymphatic invasion (ly (+) ). Concerning the macroscopic types, six (85.7%) patients in the positive group had the depressed element.<br>Accordingly, these results suggest that those 3 factors, namely cancer deeper the than sm 2. ly (+) and depressed factor, were likely high risk factors for lymph node metastasis of colorectal cancers with submucosal invasion.<br>Based on these results, resection of primary tumor with lymph node dissection of further than n 2 appears to be indicated for patients either with cancer invaded SM 2' or more at preoperative examination or with histological cancer invasion to sm 2 or more or ly (+) after polypectomy.

収録刊行物

被引用文献 (1)*注記

もっと見る

参考文献 (19)*注記

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ