Barrett食道を合併し粘液癌,印環細胞癌,腺癌を共存した食道癌の1例

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  • A CASE OF ESOPHAGEAL CANCER WITH BARRETT'S ESOPHAGUS IN WHICH MUCINOUS CARCINOMA, ADENOCARCINOMA, AND SIGNET-RING CELL CARCINOMA COEXISTED

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This paper presents an interesting case of esophageal cancer with Barrett's esophagus in which mucinous carcinoma, adenocarcinoma and signet-ring cell carcinoma coexisted through the esophagus.<br> A 77-year-old man was admitted to the hospital because of dysphagia and cough. Examination revealed a stenosis over the entire circumference of the Iu-Ei regions and a hiatal hernia of the esophagus. Histological diagnosis of biopsied specimen was advanced esophageal cancer composed of mutinous carcinoma, tubular adenocarcinoma and signet-ring cell carcinoma concomitantly.<br> Subtotal esophagectomy, lymph nodes dissection of the thoracic and abdominal region, reconstruction using gastric tube through intrathoracic route, and a cholecystectomy were performed. Histologically, mucinous carcinoma was present in the Barrett's epithelium, with coexisting tubular adenocarcinoma and signet-ring cell carcinoma. The invasion depth of the tumor was adventitia of the esophagus. After the operation, a radiation therapy was added. The patient was discharged from the hospital on 107-hospital day. No evidence of recurrence has been observed, as of 9 months after the operation.<br> To our knowledge, there has been only one case of esophageal cancer composed of mucinous carcinoma, tubular adenocarcinoma, and signet-ring cell carcinoma, concomitantly. This extremely rare case is presented.

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