Giant Hemangioma with Coagulopathyの4症例(Kasabach-Merritt Syndrome)

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タイトル別名
  • Four Caces of Giant Hemangioma with Coagulopathy (Kasabach-Merritt Syndrome)
  • Giant hemangioma with coagulopathy ノ 4 ショウレイ Kasabach-Merritt syndrome

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抄録

Four cases of giant hemangioma with coagulation abnomalities were observed. The tumors appeared at epigastric region in 2 mons. old female, at right shoulder in 2 mons. female, at lumbar region in 5 mons. old male and at left trunk in 1 yr old children.<br>Extensive coagulation studies were carried out in all cases thrombocytopenia (100,000/cmm), low fibrinogen concentration (200 mg/dl) and increased fibrinolysis (thrombin time, euglobulin lysis time or fibrin-fibrinogen degredation product) were observed.<br>Three infant cases were treated with conventional deep X-ray and or electron radiation therapy up to 540-1700 R for 1-3 weeks the treatment resulted in decrease in the size of tumors and the coagulation abnormalities were corrected to normal.<br>One case of 1 yr old girl revealed severe hemorrhagic tendency due to primary fibrinolytic activity after surgical procedure to the tumor. Antifibrinolytic therapy with t-AMCHA etc. was followed by significant improvement of hemorrhages.

収録刊行物

  • 臨床血液

    臨床血液 14 (10), 1046-1053, 1973

    一般社団法人 日本血液学会

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