壁外に大きく発育した食道神経鞘腫の1例

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  • A CASE REPORT OF NEURINOMA OF THE ESOPHAGUS

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A 52-year-old woman was admitted because of dysphagia and an oppressive feeling in the chest. Chest X-ray, esophagogram, esophagoscopy, EUS, CT, MRI, bronchoscopy and bronchial artery angiography findings led to a diagnosis of middle to posterior mediastinal tumor (bronchogenic cyst). At surgery, a mass originating in the muscle coat of the esophagus was identified and successfully removed along with a part of the esophageal mucosa. The resected specimen was a solid mass and 7×5×5cm in size. Microscopically, the tumor was composed of spindle cells in irregular fascicles, reminiscent of Antoni A type tissue. Immunohistochemically, tumor cells were positive for S-100 protein staining but negative for muscle specific actin (HHF35) staining and desmin staining. The final diagnosis was neurinoma of the esophagus.<br> Neurinoma of the esophagus is an extremely rare disease. To our knowledge, this is the seventh case of neurinoma of the esophagus reported in the Japanese literature.

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