多剤耐性黄色ブドウ球菌の患者側,細菌側および投与薬剤側の多因子によるクラスター分析

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  • MULTI-DRUG RESISTANT STAPHYLOCOCCUS AUREUS -A CLUSTER ANALYSIS USING FACTORS OF PATIENTS, BACTERIA AND DRUGS-

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Nosocomial propagation of multidrug-resistant Staphylococcus aureus was investigated in patients who underwent gastroenterologic operations. A cluster analysis was attempted to clarify the association of factors among 32 patients, 204 bacterial isolates, and drugs administered. The results showed that first-and second-generation cephalosporins, penicillins, and aminoglycosides were associated with increased resistance. Drugs of each group were given for an average of 5-9 days until the detection of the bacteria.<br> The results suggest that the use of first-and second-generation cephalosporins and penicillins during gastroenterologic operations was related with increased resistance and thus encourage to minimize their prophylactic administration.

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