A CASE OF ADULT MESOBLASTIC NEPHROMA

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  • 成人発生のmesoblastic nephromaの1例

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Abstract

This paper describes a case of adult mesoblastic nephroma (AMN) which is a very rare benign hamartoma of the kidney. A 44-year-old man was seen at the hospital because of back and right flank dull pain. Imaging method revealed a right upper abdominal mass and he underwent a right nephrectomy. Macroscopical examination revealed a 10.5×9.5×6.0cm, soft and expansive growth and on section homogeneous and solid tumor yellow-white in color replaced the upper side of the kidney. And it had sharply marginal separation to the normal kidney in spite of no capsule. Histopathologically, the tumor composed of spindle and/or polygonal shape nuclear and fibrotic bundle (Desmin+, MSA+, S100-protein-), smooth muscle cell, vesel (HMB-45-), fat cell and tubular or cystic epithelium resembled urinary tubules (CAM5.2+) and each component concomitantly existed in the entire tumor. These findings suggest that AMN is a very slowly growing congenital mesoblastic nephroma and its epithelial component belonged to the tumor elements. Moreover, the smooth muscle of vessels bore no relation to immature melanosome which is commonly seen with angiomyolipoma.

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