EVALUATION OF HEPATECTOMY FOR HEPATIC METASTASES OF COLORECTAL CANCER

• YAMASHIRO Kazuhiro

  First Department of Surgery, Sapporo Medical University

• SASAKI Kazuaki

  First Department of Surgery, Sapporo Medical University

• HIRATA Koichi

  First Department of Surgery, Sapporo Medical University

• EZOE Eiri

  First Department of Surgery, Sapporo Medical University

• KAMESHIMA Hidekazu

  First Department of Surgery, Sapporo Medical University

• TAKASAKA Hajime

  First Department of Surgery, Sapporo Medical University

• KATSURAMAKI Tadashi

  First Department of Surgery, Sapporo Medical University

• MUKAIYA Mitsuhiro

  First Department of Surgery, Sapporo Medical University

• KIMURA Hiromichi

  First Department of Surgery, Sapporo Medical University

• DENNO Ryuichi

  First Department of Surgery, Sapporo Medical University

Bibliographic Information

Other Title

• 肝切除を施行した大腸癌肝転移症例の検討

Abstract

Twenty-eight patients received a hepatectomy for hepatic metastases of colorectal cancer at the department from April 1984 to December 1993 were evaluated, especially for H₁ patients. We prefered hepatectomy with a surgical margin of more than 1cm. In addition, the continuous infusion therapy with 5-FU (250mg/day) into the hepatic artery was selected as a postoperative adjuvant therapy. Three-year and five-year survivals with H₁ patients resulted in 45% and 28%, respectively. None of H₂ patients survived more than three years. Recurrence was noted in 43% of H₁ patients, and about 90% of the recurrences occurred in the remnant liver after hepatic resection. There was no significant difference between synchronous and metachronous metastases or between males and females. The patients underwent accurate segmentectomy got a favorable prognosis compared with partial hepatectomy. The five-year survival rate of patients undergoing hepatectomy added postoperative chemotherapy combined with continuous hepatic arterial infusion, was 33% which was favorable compared with those added chemotherapy only, without significant.<br> We think that aggressive large resection of the liver including metastatic tumor combined with postoperative chemotherapy using hepatic arterial infusion is an effective treatment of hepatic metastases of colorectal cance for prognostic improvement.

Journal

• The journal of the Japanese Practical Surgeon Society

  The journal of the Japanese Practical Surgeon Society 57 (7), 1556-1560, 1996

  Japan Surgical Association

Keywords

• 大腸癌
• 肝転移
• 肝切除
• 動注化学療法

Details

• CRID: 1390282680292969728
• NII Article ID: 130003600068
• NII Article ID: 10008522419
• NII Book ID: AN00198696
• DOI: 10.3919/ringe1963.57.1556
• ISSN: 21892075
• ISSN: 03869776
• Web Site: http://www.jstage.jst.go.jp/article/ringe1963/57/7/57_7_1556/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1997033742
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed