極めて稀な乳腺癌肉腫と考えられた1例 A CASE OF CARCINOSARCOMA OF THE BREAST

この論文にアクセスする

この論文をさがす

著者

抄録

極めて稀な乳腺癌肉腫と考えられた1症例を経験したので報告する.症例は76歳女性.左乳房ほぼ全域にわたる10×10cm大の露出した腫瘤を認め,表面は自潰していた.対側右乳房C領域に径1cm大の転移を認めた.両側非定型的乳房切除術および左胸壁に全層皮膚移植術を施行した.組織学的に腫瘤部分は明らかに癌腫と肉腫が混在し,移行像は認められなかった.免疫染色でも両者は上皮系と間質系のマーカーによって色分けされた.骨・軟骨化生も認められなかった.以上より狭義の乳腺癌肉腫と診断した.左腋窩リンパ節転移および右乳房リンパ節転移を認めたが,転移巣では癌腫のみ認められた,乳腺癌肉腫は極めて稀であり,非常に興味深い症例と考えられた.

We have experienced a case of extremely rare carcinosarcoma of the breast. A 76-year-old woman was admitted to the hospital because of a left giant breast tumor. The tumor was 10×10cm in size and occupied the almost entire quadrants of the left breast with skin ulceration. And metastases to the left axillary lymph nodes and right breast were recognized. Bilateral modified radical mastectomies and full-thickness graft to left chest wall were performed. Histological examination revealed of ductal carcinoma and stromal sarcoma. Immunohistochemical staining was performed. The carcinoma component stained positive for keratin and epithelial membrane antigen (EMA). Vimentin was negative. The sarcoma component stained positive for Vimentin. Keratin and EMA were negative. Transitional foci between two components were not observed. And there were no metaplasia of cartilagonous and osseus type. We diagnosed this tumor was carcinosarcoma in a narrow sense. Metastases in the left axillary lymph nodes and right breast were consisted of carcinoma only. This case of breast carcinosarcoma is very rare as well as very interesting.

収録刊行物

  • 日本臨床外科医学会雑誌 = The journal of the Japanese Practical Surgeon Society

    日本臨床外科医学会雑誌 = The journal of the Japanese Practical Surgeon Society 58(9), 2005-2009, 1997-09-25

    Japan Surgical Association

参考文献:  19件中 1-19件 を表示

被引用文献:  3件中 1-3件 を表示

キーワード

各種コード

  • NII論文ID(NAID)
    10008530149
  • NII書誌ID(NCID)
    AN00198696
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    03869776
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
ページトップへ