書誌事項
- タイトル別名
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- Transparent, opaque and rough colonial variant susceptibility of Mycobacterium intracellulare to antimicrobial drugs.
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抄録
Mycobacterium avium-intracellulare complex (MAC) has 3 colonial variants-SmT with smooth, transparent, irregularly shaped colonies; SmO with smooth, opaque, dome-shaped colonies; and Rg with rough, granular, irregularly shaped colonies. These colonial variants differ in virulence in experimental animals. We compared the susceptibilities of 3 colonial variants isolated from identical M. intracellulare strain to rifampicin, rifabutin, streptomycin, kanamycin, ethambutol, isoniazid, ofloxacin, ciprofloxacin and cefoxitin, using 7 M. intracellulare strains isolated from patients with MAC pulmonary infection. SmT variants were much more resistant to tested antimicrobial drugs, except for ethambutol and isoniazid, than SmO variants. Rg variant susceptibility patterns to tested drugs proved to lie between SmT and SmO variants, indicating the importance of determining the MAC strain colony form isolated from clinical specimens in determining drug susceptibility.
収録刊行物
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- 日本化学療法学会雑誌
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日本化学療法学会雑誌 50 (4), 232-235, 2002
公益社団法人 日本化学療法学会
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詳細情報
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- CRID
- 1390282681261489536
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- NII論文ID
- 130004298113
- 10008541848
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- NII書誌ID
- AN10472127
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- ISSN
- 18845886
- 13407007
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可