MPO-ANCA-Positive Slowly Progressive Glomerulonephritis with Focal Tuft Necrosis and Crescents.

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A 37-year-old woman had been found to have proteinuria in October 1996. About 8 months later, the first renal biopsy was performed, revealing focal segmental necrotizing and crescentic glomerulonephritis. At that time, serum creatinine was 1.0 mg/dl and urinary protein 3+. In October 1999, laboratory tests revealed positivity for MPO-ANCA and a serum creatinine level of 1.42 mg/dl, anemia and proteinuria of 2+. A second renal biopsy showed almost the same histological findings. Accordingly, a diagnosis of MPO-ANCA positive glomerulonephritis was made. This patient was thought to be a rare case of MPO-ANCA-positive slowly progressive glomerulonephritis presenting focal segmental tuft necrosis and crescents.<br>(Internal Medicine 41: 458-462, 2002)

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  • Internal Medicine

    Internal Medicine 41 (6), 458-462, 2002

    一般社団法人 日本内科学会

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