Dynamic MRIによる睡眠時無呼吸患者の解析

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タイトル別名
  • Predicting the presence and the severity of obstructive sleep apnea (OSA) with MRI findings

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To identify MRI findings that can predict the presence and the severity of obstructive sleep apnea (OSA), we studied 21 cases with OSA, using Dynamic MRI to evaluate the status of the upper airway during sleep.Scans were obtained at the rate of one image per 1 to 2 sec while the patients were asleep, using mitazolam 5mg i.v. We performed a quantitative analysis of the presence of occlusions and of the narrowing of the pharyngeal airway and soft tissue and compared the distance and area in each of the epi-, meso-, and hypopharynx levels in the awake and asleep conditions, using both airway images taken with a DICOM Viewer System as data.<BR>The correlation between AHI, Mean SaO2, Lowest SaO2, Body Mass Index (BMI), and the valueof each measurement was assessed. In sleep, each distance of the airway in the epi-, meso-, andhypopharynx was significantly narrower than the value in the awake condition. The severity of AHI and SaO2 are significantly correlated with the width of the airway space at the base of the tongue andhypopharynx. Obesity is an important factor in OSA because it affects the volume of the tongue andof the soft tissue of the hypopharynx. Our data showed that is impossible to get information on thelevel of occlusion during sleep or on the severity of OSA by studying the patient in the awake condition.Therefore Dynamic MRI during sleep is useful to detect the level of occlusion during sleep and the severity of OSA, and this can assist in the treatment of OSA.

収録刊行物

  • 口腔・咽頭科

    口腔・咽頭科 13 (3), 389-394, 2001

    日本口腔・咽頭科学会

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