喉頭癌・白板症発症に関わる喫煙と血中ビタミン値の影響

• 志賀 伸之

  山形市立病院済生館耳鼻咽喉科

• 朴澤 孝治

  東北大学医学部耳鼻咽喉科学教室

• 高坂 知節

  東北大学医学部耳鼻咽喉科学教室

書誌事項

タイトル別名

• Effect of Smoking on the Serum Levels of Vitamins and on the Development of Laryngeal Cancer or Leukoplakia

抄録

It is believed that smoking causes benign or malignant neoplasms in the larynx. One of the possible mechanisms proposed is the inactivation of folic acid and vitamin B₁₂ that occurs in smokers, thus leading to malignant changes in the respiratory epithelia. The serum concentrations of folic acid and vitamin B₁₂ of various patients in our outpatient clinic have been measured, and it was shown that these are relatively low in smokers and ex-smokers within 2 years from cessation. One of the vocal cord leukoplakia patients presented has shown dramatic improvement by the treatment of halting smoking and oral supplement of folic acid and vitamin B₁₂.

収録刊行物

• Koutou (THE LARYNX JAPAN)

  Koutou (THE LARYNX JAPAN) 10 (1), 14-16, 1998

  The Japan Laryngological Association

キーワード

• leukoplakia
• smoking
• chemoprevention
• folic acid
• vitamin B<SUB>12</SUB>

詳細情報

• CRID: 1390001205461864448
• NII論文ID: 130004709838
• NII論文ID: 10008576416
• NII書誌ID: AN10200295
• DOI: 10.5426/larynx1989.10.1_14
• ISSN: 09156127
• Web Site: https://search.jamas.or.jp/link/ui/1998247435
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可