Primary Treatment for T1 and T2 Laryngeal Cancer.

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  • T1,T2喉頭癌の治療法選択のカギ  T2放射線照射による非制御例を中心に
  • T2放射線照射による非制御例を中心に

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Abstract

From 1986 to 2000, 86 patients with T1 and T2 laryngeal cancer were treated at our department. Eighty-one patients received initial radiation therapy, and salvage laryngectomy was performed for 8 patients who had residual tumor after 40 Gy radiotherapy. Four patients with glottic cancer had a resection of the true vocal cord with an Nd-YAG LASER under the microsopic observation and only one patients had with partial laryngectomy (front-lateral-laryngectomy) as an initial treatment. Five-year survival rates were 88.4% in T1, and 81.2% in T2. Five-year larynx preservation rates were 94.7% in T1, and 45.1% in T2. In T2, the five-year survival rates and larynx preservation rates were poor. Tumors extending to the anterior commissure and the subglottic space were poorly controlled by radiotherapy. We considered that bulky tumor extending to the anterior commissure and subglottic space are not an indication for simple radiotherapy and should undergo partial laryngectomy for the improvement of the larynx preservation.

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