Evaluation of the Developing Human Visual System Using Flash-Visual Evoked Potential.

• Tsuneishi Syuichi

  Department of Pediatrics, Kobe University Graduate School of Medicine

Bibliographic Information

Other Title

• 神経生理学的アプローチ　　ＶＥＰを中心に
• Flash-Visual Evoked Potential
• VEPを中心に

Abstract

Flash visual evoked potential (Flash-VEP) is easily recorded in preterm infants. However, its clinical application has not been established due to its great variability in response. Our longitudinal studies on the two components of the N1 wave facilitated peak definition and established normal ranges that are clinically valuable. The N1a (early component of the N1) peak latency decreases at about 4.6 msec/week between 30 and 40 weeks postmenstrual age.<BR>A flash-VEP study in the preterm period enables us to observe the neuronal development in the human visual system that normally proceeds in utero. Flash-VEP analyses on preterm infants demonstrated that the decrease in the N1a peak latency reflects the progress of myelination in the visual pathway according to the developmental program irrespective of preterm birth. The developmental changes of the N1 wave configuration reflect the maturation of the neuronal networks in the visual cortex, which is accelerated by extrauterine visual experience.<BR>Using improved methodology and peak denomination that we proposed, flash-VEP can be applied to preterm infants safely, and should provide us with neuro-developmental information of the human cerebrum.

Journal

• NO TO HATATSU

  NO TO HATATSU 34 (2), 141-146, 2002

  THE JAPANESE SOCIETY OF CHILD NEUROLOGY

Keywords

• 視覚発達
• 光視覚誘発電位
• 早産児
• 髄鞘化
• 胎外感覚刺激

Details

• CRID: 1390282679531286656
• NII Article ID: 130004068263
• NII Article ID: 10008591375
• NII Book ID: AN0020232X
• DOI: 10.11251/ojjscn1969.34.141
• ISSN: 18847668
• ISSN: 00290831
• PubMed: 11905010
• Web Site: https://search.jamas.or.jp/link/ui/2002199877
• Text Lang: ja
• Data Source:
  • JaLC
  • PubMed
  • CiNii Articles
• Abstract License Flag: Disallowed