Glucose-6-Phosphatase Histochemistry of Osteoarthritis

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著者

    • INABA Takashi
    • Department of Orthopedic Surgery, and Anatomy, Jichi Medical School
    • KARIYA Yusei
    • Department of Orthopedic Surgery, and Anatomy, Jichi Medical School
    • HOSHINO Yuichi
    • Department of Orthopedic Surgery, and Anatomy, Jichi Medical School
    • OOI Yoshio
    • Department of Orthopedic Surgery, and Anatomy, Jichi Medical School
    • YASHIRO Takashi
    • Department of Orthopedic Surgery, and Anatomy, Jichi Medical School
    • SAITO Takuma
    • Department of Orthopedic Surgery, and Anatomy, Jichi Medical School

抄録

A cytochemical study of glucose-6-phosphatase (G-6-Pase) was made to see the changes in mucopolysaccharide metabolism in the synovial membrane during osteoarthritis, because the tissue is thought to play an important role in synovial fluid production by providing lubrication to the wear-and-tear surface of the synovial cartilage in osteoarthritis. In normal and osteoarthritic synovial membranes, a high G-6-Pase activity was clearly demonstrated in the cisternal spaces of the rough endoplasmic reticula, especially in the B cells of the thickened synovial membrane. The existence of an AB cells intermediate in character between A and B, was noted in having a high G-6-Pase activity in the accumulated rough endoplasmic reticula in the cytoplasm as B cells do located at the deeper part of the membrane, but also whose cell surface extends to the top of the membrane surface reaching into the synovial cavity, and protrude microvilli of a ruffled border indicating a high phagocytotic activity as A cells do. The existence of the AB cell is clearly one of intermediate structure and function, contributive to the compensatory and regenerative action of the synovial membrane.

収録刊行物

  • Acta histochemica et cytochemica

    Acta histochemica et cytochemica 30(1), 93-103, 1997-02-01

    JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY

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各種コード

  • NII論文ID(NAID)
    10008606188
  • NII書誌ID(NCID)
    AA00508022
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    00445991
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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