Ether Extract of Fetal Cakf Serum Protects Cultured Rat Cortical Neurons against Glutamate Cytotoxicity

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抄録

The effects of an ether extract of fetal calf serum (EE-FCS)on glutamate-induced cytotoxicity were examined using primary cultures of rat cortical neurons. The simultaneous addition of EE-FCS and glutamate reduced glutamate cytotoxicity in a concentration-dependent manner. EE-FCS also reduced the cytotoxicity induced by <I>S</I>-nitrosocysteine, a nitric oxide (NO)donor. The findings indicate that EE-FCS contains lipid-soluble, non-peptide substances with neuroprotective actions against NO-mediated glutamate neurotoxicity.

収録刊行物

  • The Japanese journal of pharmacology

    The Japanese journal of pharmacology 73(4), 371-374, 1997-04-01

    The Japanese Pharmacological Society

参考文献:  9件中 1-9件 を表示

被引用文献:  7件中 1-7件 を表示

各種コード

  • NII論文ID(NAID)
    10008677973
  • NII書誌ID(NCID)
    AA00691188
  • 本文言語コード
    ENG
  • 資料種別
    SHO
  • ISSN
    00215198
  • NDL 記事登録ID
    4196937
  • NDL 雑誌分類
    ZS51(科学技術--薬学)
  • NDL 請求記号
    Z53-D199
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
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