Fulminant Diabetes Mellitus Associated with Pregnancy: Case Reports and Literature Review

この論文にアクセスする

この論文をさがす

著者

    • INAGAKI Takeshi
    • Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine
    • SUZUKI Naomi
    • Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine
    • SUZUKI Satoru
    • Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine
    • AIZAWA Toru
    • Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine
    • HASHIZUME Kiyoshi
    • Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine

抄録

We report two cases of type 1 diabetes mellitus fulminantly developed as diabetic ketoacidosis (DKA) at 19 weeks of gestation and immediately after delivery. Development of type 1 diabetes around pregnancy is not rare, but its fulminant development is highly uncommon. We also review the relevant literature concerning mostly Japanese cases. In our cases, the group of patients with fulminant progressive diabetes mellitus associated with pregnancy required insulin replacement therapy even after the acute period and showed high value of pancreatic exocrine enzymes, i.e. amylase, elastase, and lipase. The phenotype of this group was similar to "nonautoimmune, fulminant type 1 diabetes" described by Imagawa <i>et al</i>., where the laboratory data of type 1 diabetes-related autoantibodies showed negative. It is well known that autoimmune diseases are in good control during pregnancy. Our present finding suggests that this type of fulminant type 1 diabetes mellitus associated with pregnancy might develop as a consequence of a nonautoimmune mechanism.

収録刊行物

  • Endocrine journal

    Endocrine journal 49(3), 319-322, 2002-06-01

    The Japan Endocrine Society

参考文献:  14件中 1-14件 を表示

被引用文献:  3件中 1-3件 を表示

各種コード

  • NII論文ID(NAID)
    10008701492
  • NII書誌ID(NCID)
    AA10901436
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    09188959
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
ページトップへ