メニエール病に対する薬物治療の短期および長期評価 : 自然経過を考慮した検討 Evaluation of Effects of Treatment on Meniere's Disease on the Basis of Natural Course

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To evaluate short and long term effect of treatment on Meniere's disease, the clinical course was examined in 25 patients treated with Isosorbide compared with the natural course without any treatment in 20 patients. Vertigo, hearing level, tinnitus and disability were assessed 4 and 8 week and 1 year after the start of clinical observation for patients respectively using the number of vertigo spells, 4-frequency pure tone average at 250, 500, 1000 and 2000 Hz, 5-staged score and 4-staged score based on the guidelines of Japan society for equilibrium reseach in Meniere's disease. Vertigo and disability in the treated group improved more significantly (P<0.05) than that in the group allowed to follow the natural course without significant change in either hearing level or tinnitus 4 week after starting observation. In contrast, there is no significant differences in the improvement of all four symptoms between the natural and treated groups 8 week and 1 year following starting observation. The effect of the drug was markedly demonstrated in the initial stage of disease. Evaluation of the short and long term effect of treatment on Meniere's disease should be performed on the basis of natural course which requires further examination to establish.

収録刊行物

  • Equilibrium research

    Equilibrium research 56(6), 594-600, 1997-12-01

    Japan Society for Equilibrium Research

参考文献:  17件中 1-17件 を表示

被引用文献:  9件中 1-9件 を表示

各種コード

  • NII論文ID(NAID)
    10008710091
  • NII書誌ID(NCID)
    AN00001485
  • 本文言語コード
    JPN
  • 資料種別
    ART
  • ISSN
    03855716
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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