Pulmonary Complications in Adult Measles

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Other Title
  • 成人麻疹における呼吸器合併症の検討
  • セイジン マシン ニ オケル コキュウキ ガッペイショウ ノ ケントウ

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Abstract

The clinical features of pulmonary complications were evaluated in 15patients with adult measles diagnosed by clinical and serologic investigations. Of those 15patients, 12 were admitted because of high fever, sever anorexia and dyspnea. Almost all patients werefound to have thrombocytopenia, elevations of LDH and aminotransferase. Pulmonary infiltrates were present in only2of the12patients (16.7%) on whom chest roentgenograms were performed, but hypoxemia (PaO2<70Torr) were present in 8 of the 12patients (66.7%). Pulmonary function. tests in 8patients showed mild decrease in VC, moderate decrease in FEV1and severe decrease in V25. These findings suggest that hypoxemia in patients with normal chest radiographs may be largely caused by bronchiolitis. The observations of sequential peak flow rate measurement showed that severe pulmonary dysfunction continued for 4-5days after the onset of the rash. To avoid the development of respiratory failure, patients with measles should be carefully monitored for bacterial superinfections of the respiratory tract especially within several days after the appearance of the rash.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 73 (7), 640-645, 1999

    The Japanese Association for Infectious Diseases

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