Clinical Evaluation of Anaerobic Infections in Patients with Bronchopulmonary Infections Diagnosed by Transtracheal Aspiration

• KONISHI Mitsuru

  Second Department of Internal Medicine, Nara Medical University

• MORI Kei

  Second Department of Internal Medicine, Nara Medical University

• YOSHIMOTO Eiichiro

  Second Department of Internal Medicine, Nara Medical University

• TAKAHASHI Ken

  Second Department of Internal Medicine, Nara Medical University

• MAJIMA Toshimasa

  Second Department of Internal Medicine, Nara Medical University

• UEDA Katsuhiro

  Second Department of Internal Medicine, Nara Medical University

• MURAKAWA Koichi

  Second Department of Internal Medicine, Nara Medical University

• SAKAMOTO Masahiro

  Second Department of Internal Medicine, Nara Medical University

• MAEDA Koichi

  Second Department of Internal Medicine, Nara Medical University

• MIKASA Keiichi

  Second Department of Internal Medicine, Nara Medical University

• NARITA Nobuhiro

  Second Department of Internal Medicine, Nara Medical University

• SANO Reiko

  Central Laboratory Division, Nara Medical University Hospital

• MASUTANI Takayuki

  Central Laboratory Division, Nara Medical University Hospital

Bibliographic Information

Other Title

• 経気管吸引法 (TTA) による嫌気性菌呼吸器感染症の臨床的検討
• ケイキカン キュウインホウ TTA ニ ヨル ケンキセイ キン コキュウキ カンセンショウ ノ リンショウテキ ケントウ

Abstract

We evaluated the clinical and bacteriologic features in the patients with bronchopulmonary infections isolated anaerobes from transtracheal aspirates between April 1990 and March 1998. Some anaerobe was isolated in 42 (10.9%) in 387 patients whom we performed transtracheal aspiration (TTA), in 42 (15.7%) of 268 in whom some organism was isolated from TTA, or in 42 (16.3%) of 257 patients in whom some bacterium excluding acid-fast bacteria, fungi or mycoplasma from TTA. The isolation rate of anaerobic bacteria was 93.3% in the patients with lung abscess, 22.7% in the patients with nosocomial pneumonia, 19.4% in the patients with community-acquired pneumonia, 26.7% in the patients with acute exacerbation of chronic lower respiratory tract infection (CLRTI), 1.6% in the patients with persistent infection of CLRTI, and 3.0% in the patients with acute bronchitis, respectively. The major anaerobes, isolated from TTA, were Peptostreptococcus micros and Prevotella melaninogenica. The aerobic bacteria were isolated with anaerobic bacteria in 32 of 42 patients at the same time. The quantitive grade of colonial growth of anaerobes was equal to or more than aerobes in the patients with lung abscess and pneumonia. We mostly administrated 3rd generation cephems or carbapenems with or without clindamycin for the treatment of anaerobic infections. Fortyone of 42 patients were cured only by the therapy of antimicrobial agents, but pneumonia patient with lung cancer died in spite of adequate antimicrobial therapy. These results suggest that the anaerobic infections are important in the bronchopulmonary infections.

Journal

• Kansenshogaku Zasshi

  Kansenshogaku Zasshi 73 (7), 675-680, 1999

  The Japanese Association for Infectious Diseases

Keywords

• transtracheal aspiration
• bronchopulmonary infection
• anaerobe

Details

• CRID: 1390001205050683776
• NII Article ID: 130004112704
• NII Article ID: 10008716110
• NII Book ID: AN00047715
• DOI: 10.11150/kansenshogakuzasshi1970.73.675
• ISSN: 1884569X
• ISSN: 03875911
• NDL BIB ID: 4788443
• PubMed: 10481403
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4788443
• Web Site: https://search.jamas.or.jp/link/ui/2000005917
• Data Source:
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  • NDL
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  • PubMed
  • CiNii Articles
• Abstract License Flag: Disallowed