1997年秋に岩見沢市で流行したエコーウイルス30型無菌性髄膜炎の臨床的検討 Outbreak of Aseptic Meningitis in Iwamizawa, 1997, Caused by Echovirus 30

この論文にアクセスする

この論文をさがす

著者

抄録

平成9年9月から12月に岩見沢市で流行した無菌性髄膜炎にて入院した小児75人の臨床的検討及び, 発症時期別の発端施設もしくは自宅のマッピングを検討した.<BR>対象は1歳から13歳の平均6歳, 男児42人, 女児33人と男児に多くみられた. 臨床症状としては, 頭痛, 発熱, 嘔気/嘔吐の3大症状が80%以上, 他に咽頭痛が30%, 腹部症状が15%みられた. 入院中最高髄液細胞数は3/3-5,960/3 (m=654/3) で細胞分画は単核球が58%とわずかに多いものの広く分布した. 末梢血ではWBC2,600-15,600 (m=8,940)/μl, CRPO-10 (m=1.4) mg/dlと平均は低いものの炎症所見の高いものも含まれた. 合併症は1例に熱性けいれん, 3件2人に急性脳症/脳炎がみられた. 髄液細菌培養は全例陰性であったが, ウイルス分離で入院患者26例中4例と頭痛, 嘔吐症状のみで入院していない1例の5例の髄液上清からエコーウイルス30型がみつかった. 3カ月間に渡り発症者がみられ, その流行ピークである第3-6週において3施設の施設内流行が第3-4週にあり, その後発症流行が拡大していくのがみられた.

To investigate the clinical character of an outbreak of aseptic meningitis in Iwamizawa 1997 caused by echovirus 30, and to investigate the spreading of the outbreak, we analyzed clinical character of 75 hospitalized patients in our hospital, and mapped the patients' distribution in Iwamizawa City each week.<BR>We detected in our hospital an epidemic outbreak of acute enteroviral meningitis caused by echovirus type 30 in Iwamizawa, from September to December, 1997. Regarding the patients, there was little prevalence in males, with an average age of 6 years and a range of 0 to 13 years of age. The most constant symptoms were three major one such as headache (90%), fever up (89%), vomiting/nausea (87%), sometimes sorethroat (30%) and abdominal pain (15%). One case had a febrile convulsion temporally, and two cases had acute meningoencephalopathy andencephalitis. In the cereblospinal fluid (CSF), we found no predominance of mononuclear cell (MNC) (58%) in the differential cell count. The mean of the peak of CSF cell counts was 654/3. White blood cell (WBC) was 8940/μl, and CRP 1.4 mg/dl. None of them was detected in the bacterial culture of the CSF. Viral cultures were performed on CSF in 26 cases, Echovirus type 30 was isolated in 4 cases of hospitalized patients, and in one case with meningismus without pleocytosis. The beginning of the outbreak was observed in two kindergarten and one elementary school side by side. The peak of the whole outbreak was detected in the 3rd to 6th week, however the school spreading peak was detected in the 3rd and 4th weak, and spreading was going in the whole city.

収録刊行物

  • 感染症学雑誌 : 日本伝染病学会機関誌 : the journal of the Japanese Association for Infectious Diseases

    感染症学雑誌 : 日本伝染病学会機関誌 : the journal of the Japanese Association for Infectious Diseases 72(7), 747-752, 1998-07-20

    The Japanese Association for Infectious Diseases

参考文献:  7件中 1-7件 を表示

被引用文献:  2件中 1-2件 を表示

各種コード

  • NII論文ID(NAID)
    10008718505
  • NII書誌ID(NCID)
    AN00047715
  • 本文言語コード
    JPN
  • 資料種別
    ART
  • ISSN
    03875911
  • NDL 記事登録ID
    4536828
  • NDL 雑誌分類
    ZS9(科学技術--医学--病理学・微生物学・寄生虫学・感染・免疫学・血清学・アレルギー)
  • NDL 請求記号
    Z19-193
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
ページトップへ