A Clinical Investigation of Bacteremia for the Past Ten Years at the Second Department of Internal Medicine, Jikei University Hospital

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  • MAEZAWA Hiromi
    The Second Department of Internal Medicine, Jikei University School of Medicine
  • SAKAMOTO Mitsuo
    The Second Department of Internal Medicine, Jikei University School of Medicine
  • NAKAZAWA Yasushi
    The Second Department of Internal Medicine, Jikei University School of Medicine
  • SHINDO Nahoko
    The Second Department of Internal Medicine, Jikei University School of Medicine
  • YOSHIKAWA Kohji
    The Second Department of Internal Medicine, Jikei University School of Medicine
  • YOSHIDA Masaki
    The Second Department of Internal Medicine, Jikei University School of Medicine
  • SHIBA Kohya
    The Second Department of Internal Medicine, Jikei University School of Medicine

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Other Title
  • 当科の過去10年間における菌血症例の臨床的検討
  • 当科〔東京慈恵会医科大学内科〕の過去10年間における菌血症例の臨床的検討
  • トウ カ トウキョウ ジケイカイ イカ ダイガク ナイカ ノ カコ 10ネンカ

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Abstract

We clinically investigated a total of 288 cases of bacteremia for the past ten years, from January 1986 to December 1995, at the Second Department of Internal Medicine in the jikei University Hospital.<BR>All of the subjects who had a positive reaction to blood culture or catheter tip culture were investigated for their basic disease, complications, and detected bacteria. Malignant tumors, chronic renal failure, diabetes mellitus, and hematologic disease were frequent by noted.<BR>The cases due to primary infection were mainly respiratory organ infection or urinary tract infection, which were 47.8% of the total.<BR>In 31.3% of the total, catheter tip cultures were positive.<BR>Except for catheter related infection, Gram-positive coccus were detected in 40.3%, which was most frequent. Methicillin resistant Staphylococcus aureus (MRSA) were 8.1% and Staphylococcus epidermidis were 11.2%. In catheter related infection, Gram-positive coccus were detected in 59.9%, which was most frequent amongst them, MRSA was 17.2%, S.epidermidis was 16.2%.<BR>The mortality of bacteremia was 12.5%, mainly from hematologic diseases, immunodeficiency due to long term steroid administration etc.<BR>Accordingly, the more the advance of chemotherapy, the better the prognosis of septicemia is. Appearance of catheter related infection was unexpected frequent. Increase of immunocompromised host is thought to be one of the main factors in the outbreak of bacteremia.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 72 (8), 820-826, 1998

    The Japanese Association for Infectious Diseases

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