A Case with Chronic Active EB Virus Infection Accompanied with Pulmonary Candidiasis

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  • KARINO Takayuki
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School Kawasaki Hospital
  • NAKAMURA Junichi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School Kawasaki Hospital
  • FUJITA Kazue
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School Kawasaki Hospital
  • KOBASHI Yoshihiro
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School Kawasaki Hospital
  • YANO Tatsutoshi
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School Kawasaki Hospital
  • OKIMOTO Niro
    Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School Kawasaki Hospital
  • SOEJIMA Rinzo
    Kawasaki University of Medical Welfare

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Other Title
  • 慢性活動性EBウイルス感染症に肺カンジダ症を併発した1例

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Abstract

A 44-year-old woman with a history of intermittent fever for several years was admitted because of burn on her leg. On admission, she had hepatosplenomegaly and fever. Antibiotic therapy was started for bacterial infection of the burn. She lost her appetite and IVH was started. During the treatment, high fever appeared and chest X-ray films showed multiple nodular infiltrates throughout both lung fields.Candida albicans was isolated from IVH catheter culture and pulmonary candidiasis was suspected. Her fever and lung involvements were successfully treated with fluconazole. During the course, serum anti-EB-VCA-IgG antibody persisted at a hight iter and anti-EBNA antibody remained negative. EB virus DNA was detected in the peripheral blood and bone marrow. Thus, she was diagnosed as chronic active EB virus infection.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 72 (12), 1306-1310, 1998

    The Japanese Association for Infectious Diseases

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