A Case of Lyme Borreliosis Which Was Suspected to Be Caused by <I>Borrelia japonica</I> Infection in Shizuoka, Japan

• MASUZAWA Toshiyuki

  Department of Microbiology, School of Pharmaceutical Sciences, University of Shizuoka

• YANAGIHARA Yasutake

  Department of Microbiology, School of Pharmaceutical Sciences, University of Shizuoka

• FUJITA Hiroshi

  Department of Dermatology, Shizuoka General Hospital

Bibliographic Information

Other Title

• <I>Borrelia japonica</I>感染が疑われるライムボレリア症の1例
• A Case of Lyme Borreliosis Which Was Suspected to Be Caused by Borrelia japonica Infection in Shizuoka, Japan

Abstract

We report a case of Lyme borreliosis (Lyme disease) found in Shizuoka City, Japan which was suspected to be caused by Borrelia japonica infection. A 8-year-old female was bitten on her head by a tick at a camping ground, near Tamagawa, Shizuoka. The tick was removed by the patient and was discarded before species identification. After one week, lymph node swelling with tenderness developed on her left neck. She consulted a local pediatrician and was suspected to have upper respiratory infection. As oral antibiotic, cefaclor was not effective, the patient was referred to us. The patient's serum showed positive reaction with Lyme Borreliosis ELISA kit (Dakopatts, Denmark) using Borrelia burgdorferi flagellum as antigen. The serum also gave positive results with home-made ELISA to B. japonica strain IKA2, which was isolated from I. ovatus, but not with other borrelial strain isolated in the United States, Europe, and from I. persulcatus and wild rodent in Japan. In western blotting, the serum reacted with flagellin and outer surface protein A (OspA) of B. japonica. We diagnosed her as Lyme disease and got a successful result with oral penicillin, sultamicillin. From a result of our field tick survery, we have not collected I. persulcatus around the area where the patient had a tick bite. These findings indicated that Lyme disease was caused by B. japonica infection with I. ovatus bite.

Journal

• Kansenshogaku Zasshi

  Kansenshogaku Zasshi 70 (3), 264-267, 1996

  The Japanese Association for Infectious Diseases

Keywords

• Lyme borreliosis
• Borrelia japonica
• Ixodes ovatus

Details

• CRID: 1390282680023177856
• NII Article ID: 130004330457
• NII Article ID: 10008722762
• NII Book ID: AN00047715
• DOI: 10.11150/kansenshogakuzasshi1970.70.264
• ISSN: 1884569X
• ISSN: 03875911
• PubMed: 8621970
• Web Site: https://search.jamas.or.jp/link/ui/1996208271
• Data Source:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• Abstract License Flag: Disallowed