Evolution of Susceptibilities of <I>Campylobacter jejuni</I> Isolated from Diarrhoeal Cases to Fluoroquinolones in Tokyo

• TADANO Keiko

  Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health

• SHINGAKI Masao

  Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health

• SAITO Kahiko

  Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health

• TAKAHASHI Masaki

  Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health

• KAI Akemi

  Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health

• YANAGAWA Yoshitoki

  Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health

• ITOH Takeshi

  Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health

• OHTA Kenji

  Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health

• KUDOH Yasuo

  Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health

Bibliographic Information

Other Title

• 下痢患者由来<I>Campylobacter jejuni</I>のニューキノロン薬に対する薬剤感受性の年次別推移
• 下痢患者由来Campylobacter jejuniのニューキノロン薬に対する薬剤感受性の年次別推移
• ゲリ カンジャ ユライ Campylobacter jejuni ノ ニューキ
• Evolution of Susceptibilities of Campylobacter jejuni Isolated from Diarrhoeal Cases to Fluoroquinolones in Tokyo

Abstract

Recently, the increase in the number of resistant strains of Campylobacter jejuni to fluoroquinolone has been reported in European countries. We also studied antimicrobial susceptibilities of 600 clinical isolates of Campylobacter jejuni isolated during a 6 year period from 1989 through 1994 in four Tokyo Metropolitan Hospitals. The susceptibility to 6 antimicrobial agents, norfloxacin (NFLX), ofloxacin (OFLX), ciprofloxacin (CPFX), nalidixic acid (NA), erythromycin (EM) and tetracycline (TC) were examined.<BR>The overall resistant rates were as follows: NFLX, 45 strains (7.5%); OFLX, 45 strains (7.5%); CPFX, 44 strains (7.3%); NA, 62 strains (10.3%); EM, 4 strains (0.6%) and TC, 259 strains (43.2%).<BR>The number of resistant strains to fluoroquinolones and NA has increased significantly since 1993 in Japan, but the suscetibility to erythromycin has still remained the same level during the past 6 years. The susceptibility to TC was variable, and MICs gave a bimobal distribution, as pointed out previously.<BR>The resistance pattern of NFLX, OFLX, CPFX and NA were observed most frequently in those isolates.

Journal

• Kansenshogaku Zasshi

  Kansenshogaku Zasshi 70 (12), 1227-1233, 1996

  The Japanese Association for Infectious Diseases

Keywords

• Campylobacter jejuni
• fluoroquinolone
• drug resistance
• antimicrobial susceptibility

Details

• CRID: 1390282680023305600
• NII Article ID: 130004330440
• NII Article ID: 10008721817
• NII Article ID: 10008724232
• NII Book ID: AN00047715
• DOI: 10.11150/kansenshogakuzasshi1970.70.1227
• ISSN: 1884569X
• ISSN: 03875911
• ISSN: http://id.crossref.org/issn/03875911
• NDL BIB ID: 4107995
• PubMed: 9011115
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4107995
• Web Site: https://search.jamas.or.jp/link/ui/1997103449
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• Abstract License Flag: Disallowed