Synthetic Study on Neural Siglecs Ligands: Systematic Synthesis of α-Series Polysialogangliosides and Their Analogues

• Ishida Hideharu

  Department of Applied Bio-organic Chemistry

• Kiso Makoto

  Department of Applied Bio-organic Chemistry

書誌事項

タイトル別名

• Synthetic Study on Neural Siglecs Ligands. Systematic Synthesis of .ALPHA.-Series Polysialogangliosides and Their Analogues.
• Synthetic Study on Neural Siglecs Ligands Systematic Synthesis of アルファ Series Polysialogangliosides and Their Analogues
• Systematic Synthesis of α-Series Polysialogangliosides and Their Analogues

抄録

To elucidate the structure required as the ligands of neural Siglecs at the level of the sugar residue, α-series polysialogangliosides, GD1α, GT1aα and GQ1bα, were successfully synthesized. In addition, a series of GD 1α analogues which contain the modified sialic acids, were synthesized to elucidate the structure-activity relationship of the MAG ligands at the level of the functional group.

収録刊行物

• 有機合成化学協会誌

  有機合成化学協会誌 58 (11), 1108-1113, 2000

  公益社団法人 有機合成化学協会

キーワード

• Organic Chemistry

詳細情報

• CRID: 1390001205277078144
• NII論文ID: 10008822408
• NII書誌ID: AN0024521X
• DOI: 10.5059/yukigoseikyokaishi.58.1108
• ISSN: 18836526
• ISSN: 00379980
• NDL書誌ID: 5549752
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I5549752
• 本文言語コード: en
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