新皮質ニューロンEPSPの確率的減衰挙動 : Markram-Tsodyks 実験の解析 Stochastic Depression Behavior of EPSPs in the Neocortical Neurons : Analysis of the Markram-Tsodyks Experiments

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著者

    • 小山 英之 KOYAMA Hideyuki
    • 大阪府立大学工学部数理工学科 Department of Mathematical Sciences, Faculty of Engineering, Osaka Prefecture University
    • 藤江 徳雄 FUJIE Norio
    • 大阪府立大学工学部数理工学科 Department of Mathematical Sciences, Faculty of Engineering, Osaka Prefecture University
    • 宮崎 孝昭 MIYAZAKI Takaaki
    • 大阪府立大学工学部数理工学科 Department of Mathematical Sciences, Faculty of Engineering, Osaka Prefecture University
    • 大島 裕子 OSHIMA Hiroko
    • 大阪府立大学工学部数理工学科 Department of Mathematical Sciences, Faculty of Engineering, Osaka Prefecture University

抄録

Stochastic depression behavior of EPSPs which has been investigated experimentally by Markram and Tsodyks is analyzed using a probabilistic postsynapse model involving a 2-state receptor type and the Morris-Lecar equations. The analysis explains the depression and stationary properties of EPSPs on the basis of saturation and recovery characteristics of the receptor mechanisms. Furthermore, the "after pairing effect" is caused by changes in the receptor sensitivity, according to the present model. The model predictions with various action potential frequencies are in good agreement with the experimental results.

収録刊行物

  • 日本神経回路学会誌 = The Brain & neural networks

    日本神経回路学会誌 = The Brain & neural networks 7(4), 115-120, 2000-12-05

    Japanese Neural Network Society

参考文献:  11件中 1-11件 を表示

各種コード

  • NII論文ID(NAID)
    10008841737
  • NII書誌ID(NCID)
    AA11658570
  • 本文言語コード
    JPN
  • 資料種別
    ART
  • ISSN
    1340766X
  • データ提供元
    CJP書誌  J-STAGE 
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