Bioactivity of M_2O-TiO_2-SiO_2 (M=Na,K) Glasses : An In vitro Evaluation

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The formation of biologically active bonelike apatite on the surfaces of glasses and glass-ceramics is an essential condition for their bonding living bone. In the present study, apatite formation on the surfaces of M<sub>2</sub>O–TiO<sub>2</sub>–SiO<sub>2</sub> (M = Na, K) glasses was examined in a simulated body fluid with ion concentrations nearly equal to those of human blood plasma in order to evaluate their bioactivity. While none of the Na<sub>2</sub>O–TiO<sub>2</sub>–SiO<sub>2</sub> ternary glasses formed the surface apatite, K<sub>2</sub>O–TiO<sub>2</sub>–SiO<sub>2</sub> glasses, not only as SiO<sub>2</sub>-rich glasses but also as TiO<sub>2</sub>-rich glasses, formed the apatite. The alkali ions in the glasses exchanged with H<sub>3</sub>O<sup>+</sup> ions in the fluid. The TiO<sub>2</sub>-rich or SiO<sub>2</sub>-rich hydrogel which was formed on the surfaces of the glasses induced apatite nucleation. The increased degree of the supersaturation of the fluid with respect to the apatite due to the increase in pH provided favorable conditions for apatite nucleation. This indicates that alkali titanates as well as alkali silicates can be basic components of bioactive glasses.

収録刊行物

  • Bulletin of the Chemical Society of Japan

    Bulletin of the Chemical Society of Japan 69(8), 2387-2394, 1996-08-15

    The Chemical Society of Japan

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  • CaO-SiO_2-P_2O_5系ガラスの生体活性の組成依存性 : in vitro 評価

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各種コード

  • NII論文ID(NAID)
    10008907816
  • NII書誌ID(NCID)
    AA00580132
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    00092673
  • NDL 記事登録ID
    4060564
  • NDL 雑誌分類
    ZP1(科学技術--化学・化学工業)
  • NDL 請求記号
    Z53-B35
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
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