Structure-Activity Relationship of Norzoanthamine Exhibiting Significant Inhibition of Osteoporosis

この論文にアクセスする

この論文をさがす

著者

抄録

Norzoanthamine is a zoanthamine-type alkaloid from the colonial zoanthid <i>Zoanthus</i> sp. Norzoanthamine hydrochloride, which suppresses the decrease in bone weight and strength in ovariectomized mice, could be a good candidate for an osteoporotic drug. Although the relative configuration of norzoanthamine was established based on an X-ray crystallographic analysis, the absolute stereochemistry of norzoanthamine remains unclear. To investigate their biogenesis and mechanisms of biological action, we conducted chemical and spectroscopic studies to determine the absolute configuration of norzoanthamines.

収録刊行物

  • Bulletin of the Chemical Society of Japan

    Bulletin of the Chemical Society of Japan 71(4), 771-779, 1998-04-15

    The Chemical Society of Japan

参考文献:  33件中 1-33件 を表示

  • <no title>

    JOSEFSSON B.

    Marine Natural Products, Chemical and Biological Perspective 1, 1980

    被引用文献1件

  • <no title>

    WESTLEY J. W.

    Polyether Antibiotics, Natural Occurring Acid Ionophores 2, 1983

    被引用文献1件

  • <no title>

    COREY E. J.

    The LOGIC of CHEMICAL SYNTHESIS, 1989

    被引用文献6件

  • <no title>

    BAKER J. T.

    Handbook of Marine Science, Compounds from Marine Organisms 1, 1976

    被引用文献1件

  • <no title>

    BAKER J. T.

    Handbook of Marine Science, Compounds from Marine Organisms 2, 1981

    被引用文献1件

  • <no title>

    FAULKNER D. J.

    Nat. Prod. Rep. 1, 251, 1984

    被引用文献4件

  • <no title>

    FAULKNER D. J.

    Nat. Prod. Rep. 1, 551, 1984

    被引用文献3件

  • <no title>

    FAULKNER D. J.

    Nat. Prod. Rep. 3, 1, 1986

    被引用文献5件

  • <no title>

    FAULKNER D. J.

    Nat. Prod. Rep. 5, 613, 1988

    被引用文献5件

  • <no title>

    MOORE R. E.

    Prog. Chem. Org. Nat. Prod. 48, 81, 1985

    被引用文献1件

  • <no title>

    HIRATA Y.

    Handbook of Natural Toxins: Marine Toxins and Venoms 3, 241, 1988

    被引用文献1件

  • <no title>

    NAKANISHI K.

    Biomedical Importance of Marine Organisms 59, 1988

    被引用文献1件

  • <no title>

    YOKOYAMA A.

    J. Biochem. 104, 184, 1988

    被引用文献4件

  • <no title>

    TACHIBANA K.

    J. Am. Chem. Soc. 103, 2469, 1981

    被引用文献7件

  • <no title>

    PAUL V. J.

    Biomedical Importance of Marine Organisms 23, 1988

    被引用文献1件

  • <no title>

    MUNRO M. H. G.

    Bioorganic Marine Chemistry 1, 93, 1987

    被引用文献1件

  • <no title>

    FAUTIN D. G.

    Biomedical Importance of Maine Organisms, 1988

    被引用文献1件

  • <no title>

    FUKUZAWA S.

    Heterocycl. Commun. 1, 207, 1995

    被引用文献5件

  • <no title>

    RAO C. B.

    J. Am. Chem. Soc. 106, 7983, 1984

    被引用文献6件

  • <no title>

    RAO C. B.

    J. Org. Chem. 50, 3757, 1985

    被引用文献6件

  • <no title>

    RAO C. B.

    Heterocycles 28, 103, 1989

    被引用文献5件

  • <no title>

    ATTA-UR-RAHMAN K. A.

    Tetrahedron Lett. 30, 6825, 1989

    被引用文献3件

  • <no title>

    TURNER C. H.

    Bone 14, 595, 1993

    被引用文献2件

  • <no title>

    KURAMOTO M.

    38th Symposium on the Chemistry of Natural Products, 79-84, 1996

    被引用文献1件

  • <no title>

    KURAMOTO M.

    Tetrahedron Lett. 38, 5683, 1997

    被引用文献6件

  • <no title>

    OHTANI I.

    J. Am. Chem. Soc. 113, 4092, 1991

    被引用文献40件

  • <no title>

    YAMAGUCHI K.

    J. Bone. Miner. Matab.

    被引用文献1件

  • <no title>

    MATSUDA T.

    Eur. J. Immunol. 18, 951, 1988

    被引用文献2件

  • <no title>

    BREITMAIER E.

    Carbon-13 NMR Spectroscopy, 186-189, 1990

    被引用文献1件

  • <no title>

    UEMURA D.

    Bioorganic Marine Chemistry 4, 1, 1991

    被引用文献3件

  • <no title>

    UEMURA D.

    J.Am.Chem.Soc. 117, 1155, 1995

    被引用文献9件

  • <no title>

    FAULKNER D. J.

    Nat. Prod. Rep. 4, 539, 1987

    DOI 被引用文献10件

  • Increased bone formation in osteocalcin-deficient mice

    DUCY P.

    Nature 382, 448-452, 1996

    DOI 被引用文献58件

被引用文献:  2件中 1-2件 を表示

各種コード

  • NII論文ID(NAID)
    10008930281
  • NII書誌ID(NCID)
    AA00580132
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    00092673
  • NDL 記事登録ID
    4462517
  • NDL 雑誌分類
    ZP1(科学技術--化学・化学工業)
  • NDL 請求記号
    Z53-B35
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
ページトップへ