The Neuropathology of Dementia.

• OGATA Jun

  National Cardiovascular Center

Bibliographic Information

Other Title

• 痴呆性疾患の病理
• キョウイク コウエン チホウセイ シッカン ノ ビョウリ

Abstract

This study discusses pathological changes seen in the brains of patients with Alzheimer's disease (AD) and vascular dementia (VaD), representative types of dementia. The cardinal pathological changes in AD consist of neurofibrillary tangles and senile plaques. In regards to VaD, the pathological changes in the brain in BD (which is a typical example of VaD) indicate that lacunae and subcortical white matter changes result from small vessel disease. For the purpose of research and treatment of patients suffering from such forms of dementia, diagnostic criteria are needed in order to standardize clinical and pathological diagnoses. Problems in establishing such diagnostic criteria are discussed. In addition, various vascular lesions complicating AD and BD were shown to aggravate cognitive and neurological functions.

Journal

• THE JAPANESE JOURNAL OF COMMUNICATION DISORDERS

  THE JAPANESE JOURNAL OF COMMUNICATION DISORDERS 17 (3), 165-170, 2000

  Japanese Association of Communication Disorders

Keywords

• Alzheimer's disease
• vascular dementia
• small-vessel disease
• Binswanger's disease

Details

• CRID: 1390282679301178496
• NII Article ID: 10008982152
• NII Book ID: AN10091280
• DOI: 10.11219/jjcomdis1983.17.165
• ISSN: 18847056
• ISSN: 09128204
• NDL BIB ID: 5632355
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I5632355
• Web Site: https://search.jamas.or.jp/link/ui/2001144120
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • CiNii Articles
• Abstract License Flag: Disallowed