CBDCA・5FU®併用術前放射線治療の効果-組織照射効果と副作用発現について-

• 横溝 道範

  秋田大学医学部耳鼻咽喉科学教室

• 岡本 美孝

  山梨医科大学耳鼻咽喉科学教室

• 多田 裕之

  秋田大学医学部耳鼻咽喉科学教室

• 松崎 全成

  山梨医科大学耳鼻咽喉科学教室

• 石川 和夫

  秋田大学医学部耳鼻咽喉科学教室

• 戸川 清

  秋田大学医学部耳鼻咽喉科学教室

書誌事項

タイトル別名

• Evaluation of Preoperative Radiation Therapy in Combination with Low Dose Carboplatin and 5FU
• CBDCA・5FU併用術前放射線治療の効果--組織内照射効果と副作用発現について
• CBDCA 5FU ヘイヨウ ジュツゼン ホウシャセン チリョウ ノ コウカ

抄録

A comparative study was performed to evaluate difference in the histological effects and side effects between a group of tongue cancer and hypopharyngeal cancer patients treated with 5FU (250 mg×3days/week) and 60 Gy radiation, and those treated with CBDCA (50-80mg×lday/week) followed by 5FU (250 mg×2days/week) and 40 Gy radiation. In the tongue cancer patients, there was no significant change in histological effects according to Shimosato's classification system. A decrease in leukocytes was found in the CBDCA group, which was not statistically significant. In cases with hypopharyngeal cancer, the number of leukocytes was significantly decreased in the CBDCA group. However the number of platelets and degree of stomatitis was not significantly altered.

収録刊行物

• 耳鼻咽喉科臨床　補冊

  耳鼻咽喉科臨床　補冊 1997 (Supplement94), 201-205, 1997

  The Society of Practical Otolaryngology

キーワード

• carboplatin
• radiation
• head and neck cancer

詳細情報

• CRID: 1390282680504266752
• NII論文ID: 10009235892
• NII書誌ID: AN10020883
• DOI: 10.5631/jibirinsuppl1986.1997.supplement94_201
• NDL書誌ID: 4336308
• ISSN: 09121870
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4336308
• Web Site: https://search.jamas.or.jp/link/ui/1998102380
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可