ナイアシン欠-トリプトファン制限食投与ラットの6-アミノニコチンアミドの最少作用量

書誌事項

タイトル別名
  • The Minimum Amount of 6-Aminonicotinamide Affecting the Growth of Rats Fed with a Niacin-free, Tryptophan-limiting Diet
  • ナイアシン ケツ トリプトファン セイゲンショク トウヨ ラット ノ 6 アミ

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抄録

6-Aminonicotinamide is a pellagragenic compound. In this study, the minimum amount of 6-aminonicotinamide affecting the growth of rats fed with a niacin-free, tryptophan-limiting diet was examined. The rats were fed ad libitum with the diet containing 50, 70, 100, 500 or 1000ppm 6-aminonicotinamide for 14 days, and body weight and food intake were measured daily. The lowest dose showing clear growth retardation and decrease in food intake was 500ppm 6-aminonicotinamide. The average intake of 6-aminonicotinamide in this group was 0.45mg/kg body weight/day.

収録刊行物

  • 食品衛生学雑誌

    食品衛生学雑誌 36 (1), 82-84_1, 1995

    公益社団法人 日本食品衛生学会

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